The hmr command fails when methylation levels are at extremes #251
Description
Describe the bug
When methylation levels are either 0 or 1 at all sites, there seems to be a bug.
To Reproduce
This was found by simulating a methylome with those extremes: a set of intervals used as HMRs was used and sites within the HMRs had methylation level of 0 while those outside had 1.0. Then reads were simulated with high coverage (e.g., 200).
Expected behavior
If the estimation is not possible, or does not make sense, then it should be reported.
Desktop (please complete the following information):
Ubuntu 22.04